Success of Glucophage for Infertility - Make Your Mind Up!
Success of Glucophage for infertility.
Glucophage is the brand name of Metformin. Its class of drug is known as biguanide, it exerts it’s effect mainly by decreasing gluconeogenesis ((abbreviated GNG) is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as lactate, glycerol, and glucogenic amino acids).
How it works
Glucophage is an oral medication used for Type 2 diabetes and helps the body respond better to insulin; this then helps the body metabolize the sugar glucose.
Glucophage for infertility is used quite frequently by doctors as it increases muscle cell sensitivity to insulin. You need insulin to carry the glucose (which is like fuel) to be delivered to your cells to be either stored, burned. Glucophages role is to help your body move the glucose around it with smaller amounts of insulin. If you have loads of insulin just hanging around the body you are known as insulin resistant.
Glucophage for infertility,
The female reproductive system, particularly the ovaries, requires insulin to work properly. When there is an excess of insulin in the body, the ovaries may not function normally. Thus, there is a basic relationship between insulin and pregnancy. This relationship becomes especially important for women with PCOS.
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(Polycystic Ovarian Syndrome) is a common cause of infertility. The ovaries of women with PCOS contain many small cysts, hence the name “polycystic.” Women with PCOS often do not ovulate regularly and have irregular menstrual cycles. In terms of glucophage for infertility it again can improve your chances of conceiving, but if you have been diagnosed with PCOS there is an
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Many physicians and fertility experts attempt to treat PCOS with a drug called clopimhene, brand name
which helps to induce ovulation. In recent years, Glucophage has been used, either with or without Clomid, to help produce ovulation in women with PCOS, but the results showed that a combination of the two was similar to the success rate of Clomid alone.
Although Glucophage assists the body with responding to and managing its insulin; in turn, this helps the ovaries function more regularly, and creates a more regular ovulation cycle. This assists greatly when trying to conceive.Some studies have suggested that the use of Glucophage also can help reduce the risk of miscarriage. Additionally, the use of Glucophage may reduce the risk of gestational diabetes, and may delay or prevent the onset of Type 2 diabetes.
Side effects of Glucophage can include abdominal pain or cramping, discomfort, and nausea, also general tiredness or malaise. The use of Glucophage may inhibit the absorption of Vitamin B12. Your physician may recommend vitamin supplements and/or dietary changes to accompany the use of Glucophage.
Safety, It has yet to be established as to be used safely during pregnancy.