Is there a link between Caffine and Infertility?






Much has been written about caffine and infertility and how caffine affects fertility. There have been numerous clinical trials and observational studies conducted and reviewed by the major medical bodies in both the US and UK and the outcomes have been always mixed or inconclusive. Some studies have suggested that high levels of caffine (more than 300mg/day) over three cups a day may make it harder to conceive, but these findings are just not proven and even low to moderate caffine consumption (less than 300mg/day) does not seem to reduce a woman’s chance of becoming pregnant.

Many studies have examined the effects of caffine and infertility combined and most have found that moderate caffine intake does not affect fertility or increase the chance of having a miscarriage or a baby with birth defects; although some studies did find a relationship between caffeine intake and fertility or miscarriages. However, most of those studies were judged to be inadequate because they did not consider other lifestyle factors that could contribute to infertility or miscarriages.

The US organization OTIS (Organization of Teratology Information Specialists) stated that there is no evidence that caffeine causes birth defects in humans.

The American Academy of Pediatrics recommends that nursing women should limit their caffine intake, but states that no harm is likely to occur in a nursing child whose mother drinks one cup of coffee a day.

Numerous studies have been conducted to determine the effects of caffine and infertility in women, but non can confirm a detrimental effect due to either other factors from the study such as stress.

In 1988 a study suggested that caffeine, equivalent to the amount consumed in 1 to 2 cups of coffee daily, might decrease female fertility. However, the researchers acknowledged that delayed conception could be due to other factors they did not consider, such as exercise, stress or other dietary habits. Since then, larger, well-designed studies have failed to support the 1988 findings.

In another study 1990, researchers at the Centers for Disease Control and Prevention and Harvard University examined the association between the length of time to conceive and consumption of caffeinated beverages. The study involved more than 2,800 women who had recently given birth and 1,800 women with the medical diagnosis of primary infertility. Each group was interviewed concerning caffeine consumption, medical history and lifestyle habits. The researchers found that caffeine consumption had little or no effect on the reported time to conceive in those women who had given birth. The result was there was no risk association with caffine and infertility.

Supporting those findings, a 1991 study of 11,000 Danish women examined the relationship among number of months to conceive, cigarette smoking

and coffee and tea consumption. Although smokers who consumed eight or more cups of coffee per day experienced delayed conception, nonsmokers did not, regardless of caffeine consumption. So this trial support the 1990 trial that the relationship between caffine and infertility is indistinct.

A study of 210 women, published in the American Journal of Public Health in 1998, examined the differences in fertility associated with consumption of different caffeinated beverages. This study, prompted by an inconsistency in previously reported findings, did not find a significant association between total consumption of caffine and infertility. In fact, the researchers found that women who drank more than one-half cup of tea per day had a significant increase in fertility. This was particularly true with caffeine consumption in the early stages of a woman's attempt at conception. The caffeinated tea and fertility correlation was supported by a 1994 study; however, those women had significantly higher consumption levels.

OTIS in 2001 reviewed the studies examining caffine and infertility and concluded that, "Low to moderate caffeine consumption (<300 mg/day) does not seem to reduce a woman's chance of becoming pregnant."

Many women, especially those of childbearing age, are concerned about consuming too much caffeine. From reproductive effects to osteoporosis, scientists worldwide have studied the effects of caffeine on women’s health. Below are some facts about caffeine that address common concerns and misperceptions about caffine and infertility and women’s health. When taken together, the collective research supports moderate consumption of caffine (up to 300 mg/day or three cups of coffee) for women, including those who are pregnant or breastfeeding.

Caffeine is safe though and this has been fully verified; Caffeine is a naturally occurring substance found in the leaves, seeds or fruits of at least 63 plant species worldwide.

In 1958, the U.S. Food and Drug Administration (FDA) classified caffeine as Generally Recognized As Safe (GRAS). In 1987, the FDA reaffirmed its position that moderate caffeine intake produced no increased risk to health. In addition, both the American Medical Association and the American Cancer Society have statements confirming the safety of moderate caffeine consumption.

A 2010 review of epidemiological literature on caffeine and infertility health published between January 2000 and December 2009 found that the weight of evidence does not support a cause-and-effect relationship between caffeine consumption and adverse reproductive or perinatal outcomes. (Immediately before and after birth) (Peck, et al., 2010) So only recently again the relationship between caffine and infertility is still unfounded.

Moderate caffeine consumption does not affect a woman's chances of getting pregnant. In 2003 review of the research on caffine and fertility showed that consumption of caffeine at or below 300 mg per day did not reduce fertility.

For women who are pregnant or trying to become pregnant, consuming moderate amounts of caffeine does not affect their chances of miscarriage.

Several women's health organizations agree that moderate caffine consumption is safe for pregnant women. OTIS states in informational resources on their Web site that consuming up to 300 mg/day of caffeine does not affect miscarriage. The March of Dimes recently revised their recommendation for caffeine during pregnancy to 200 mg/day. In addition, in 2010 the American College of Obstetricians and Gynecologists (ACOG) published a position statement which states that moderate caffeine intake (less than 200 milligrams a day or one cup of coffee per day) does not increase a pregnant woman's risk of miscarriage or preterm birth. So again recently caffine and infertility are showing not to impact of fertility

Caffine is a stimulant that is found in drinks such as tea, coffee and cola’s, sodas and sports drinks. This should be remembered when buying all those soft drinks that we love.

Caffeinated drinks

People who are concerned about caffine and infertility problems should be informed that there is no consistent evidence of an association between consumption of caffeinated beverages (tea, coffee, colas and sports drinks) and fertility problems. Obviously caffine is present in coffee, tea, colas and chocolate, but the link between caffine and female infertility is inconsistent. (1, 3–14).

One study addressing the question of caffeine and infertility in males, showed no evidence of an association between caffeine intake and poor semen parameters. However, the combination of coffee drinking with smoking diminished sperm motility and increased the proportion of dead sperm. (2).

In an observational study of affects caffine and infertility , caffine consumption (over 2–50 mg/day versus 0–2 mg/day; 100 mg caffine in one cup of coffee) during a lifetime (i.e., usual intake) and during the week of initial visit for infertility were strong risk factors for not achieving a live birth in women undergoing IVF Treatment or GIFT, after adjusting for smoking, alcohol, age, race, education, parity, types of infertility, types of procedure, number of assisted reproduction attempts and number of embryos transferred. (15). This study also reported an association between maternal coffee consumption and decreased infant gestational age. (15).

Recommendations for Fertility and caffine intake.

If you are concerned about your fertility and caffeine intake there is no consistent evidence of an association between consumption of caffeinated beverages (tea, coffee and colas and sports drinks) and fertility problems.

But couples should be informed that caffeine consumption has adverse effects on the success rates of assisted reproduction procedures, including in vitro fertilization treatment. So keep caffeine out of the equation, try decaffeinated drinks.

If you have been trying to get pregnant for sometime without success, try limiting your total intake of caffine in coffee, tea, cola and cocoa, and associated products, such as chocolate. This is especially relevant if you regularly consume more than 300mg a day put together. Plus remember that many other foodstuffs have caffine or cocoa in them, so it all adds up.

The current recommendations are to keep your caffine intake at these lower levels once you become pregnant. For well being and healthy living and getting baby-fit it makes sense to reduce your intake while you're trying to conceive, so to get pregnant and resolve your concerns Click here caffine and infertility resolved in one. Another good practice would be to reduce your caffine and infertility concerns is to drink only de-caffinated drinks, believe me after a while you can not tell the difference nowadays, or try some of the great tasting herbal infusions.


References.


1. Hakim RB, Gray RH, Zacur H. Alcohol and caffeine consumption and decreased fertility. Fertil Steril 1998;70:632–7.
2. Marshburn PB, Sloan CS, Hammond MG. Semen quality and association with coffee drinking, cigarette smoking, and ethanol consumption. Fertil Steril 1989;52:162–5.
3. Wilcox A, Weinberg C, Baird D. Caffeinated beverages and decreased fertility. Lancet 1988;2:1453–6.
4. Christianson RE, Oechsli FW, van den Berg BJ. Caffeinated beverages and decreased fertility. Lancet 1989;1:378.
5. Joesoef MR, Beral V, Rolfs RT, Aral SO, Cramer DW. Are caffeinated beverages risk factors for delayed conception? Lancet 1990;335:136–7.
6. Olsen J. Cigarette smoking, tea and coffee drinking, and subfecundity. Am J Epidemiol 1991;133:734–9.
7. Hatch EE, Bracken MB. Association of delayed conception with caffeine consumption. Am J Epidemiol 1993;138:1082–92.
8. Florack EIM, Zielhuis GA, Rolland R. Cigarette smoking, alcohol consumption, and caffeine intake and fecundability. Prev Med 1994;23:175–80.
9. Alderete E, Eskenazi B, Sholtz R. Effect of cigarette smoking and coffee drinking on time to conception. Epidemiology 1995;6:403–8.
10. Stanton CK, Gray RH. Effects of caffeine consumption on delayed conception. Am J Epidemiol 1995;142:1322–9.
11. Bolumar F, Olsen J, Rebagliato M, Bisanti L. Caffeine intake and delayed conception: a European multicenter study on infertility and subfecundity. European Study Group on Infertility Subfecundity. Am J Epidemiol1997;145:324–34.
12. Curtis KM, Savitz DA, Arbuckle TE. Effects of cigarette smoking, caffeine consumption, and alcohol intake on fecundability. Am J Epidemiol 1997;146:32–41.
13. Caan B, Quesenberry CP Jr, Coates AO. Differences in fertility associated with caffeinated beverage consumption. Am J PublicHealth 1998;88:270–4.
14. Jensen TK, Henriksen TB, Hjollund NH, Scheike T, Kolstad H, Giwercman A, et al. Caffeine intake and fecundability: a follow-upstudy among 430 Danish couples planning their first pregnancy. Reprod Toxicol 1998;12:289–95.
15. Klonoff-Cohen H, Bleha J, Lam-Kruglick P. A prospective study of the effects of female and male caffeine consumption on the reproductive endpoints of IVF and gamete intra-fallopian transfer. Hum Reprod 2002;17:1746–54.